Additionally, according to the website, 303 Gallery is committed to supporting emerging and mid-career artists in their practices by providing them with a platform to showcase their work to a wider audience. The gallery's program includes solo exhibitions, group shows, and participation in major international art fairs.

303 Gallery's roster of artists includes many well-known names in the contemporary art world, such as Doug Aitken, Karen Kilimnik, Mary Heilmann, and Rodney Graham, among others. The gallery also collaborates with museums and other institutions to produce exhibitions and public art projects.

In addition to its exhibition program, 303 Gallery has published several books and catalogs featuring the work of its artists. The gallery's publications are known for their high production values and critical essays written by leading writers and curators in the art world.

Overall, 303 Gallery is recognized as one of the most important galleries in New York City, and has been instrumental in shaping the careers of many influential artists since its founding.